Fatty Liver Treatment in Singapore

Dr Thng Yongxian

Liver & Hepatopancreatobiliary (HPB) Surgeon
MBBS • MMed • MRCS (IRE) • FRCSED • FAMS

What is Fatty Liver Disease?

Fatty liver disease occurs when excess fat builds up in the liver, affecting its normal function. This condition can range from simple steatosis, where fat is present without significant inflammation, to steatohepatitis, which involves liver inflammation and damage. In more advanced cases, persistent liver injury can lead to fibrosis and cirrhosis, where healthy liver tissue is replaced by scar tissue, impairing liver function.

 

Fatty liver disease can develop silently, often without noticeable symptoms, making awareness, screening, early management, and timely treatment in Singapore especially important.

Types of Fatty Liver Disease

Non‑Alcoholic Fatty Liver (NAFLD / MASLD)

Non-Alcoholic Fatty Liver Disease (NAFLD), now more accurately referred to as Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), is linked to metabolic risk factors such as obesity, type 2 diabetes, high cholesterol, and elevated triglycerides. 

 

It can range from:

Alcoholic Fatty Liver Disease (AFLD / ALD)

This form of fatty liver, also known as alcohol-related liver disease (ALD), results from excessive alcohol consumption. Persistent alcohol intake can cause inflammation and scarring, potentially progressing to cirrhosis.

Acute Fatty Liver of Pregnancy (AFLP)

A rare and serious condition that occurs during the third trimester of pregnancy. It requires urgent medical attention to prevent complications for both mother and baby.

Risks and Silent Progression of Fatty Liver Disease

Fatty liver disease is often asymptomatic in its early stages, meaning many patients remain unaware until the condition has advanced. If left untreated, it can lead to:

How Fatty Liver is Diagnosed

Diagnosing fatty liver involves a specialist using a combination of tests to assess liver health and the extent of fat accumulation.

Fatty Liver Treatment Options in Singapore

Lifestyle and Nutrition

Lifestyle changes are the cornerstone of fatty liver management and can significantly improve liver health:

Medical Management

While there is no single drug that cures fatty liver, medications may help manage related conditions and support liver health:

Emerging Therapies and Research

New treatments are being studied for fatty liver. GLP-1 receptor agonists, such as semaglutide, have shown potential benefits for reducing liver fat and inflammation.

Fatty Liver Surgery

Surgery is considered for selected patients with obesity and severe metabolic conditions, such as type 2 diabetes, high blood pressure, or high cholesterol. Bariatric procedures can lead to significant, sustained weight loss, which in turn reduces liver fat and inflammation.

 

Surgical options include:

Gastric Bypass (Roux-en-Y)

Creates a small stomach pouch and reroutes part of the small intestine. This limits food intake and alters gut hormones, improving insulin sensitivity and promoting weight loss.

Sleeve Gastrectomy

Removes a large portion of the stomach, leaving a smaller, tube-shaped stomach that restricts food intake while supporting gradual weight reduction.

Adjustable Gastric Banding

Involves placing a band around the stomach to reduce its capacity. This is less commonly performed today but can still be an option for certain patients.

Rare Use of Liver Transplant for End-Stage Cirrhosis

In cases where fatty liver disease progresses to end-stage cirrhosis, a liver transplant may be considered, but only after all other treatment options in Singapore have been exhausted. 

 

This typically occurs when liver function deteriorates significantly, resulting in complications such as jaundice, fluid retention in the abdomen (ascites), bleeding from enlarged veins (variceal bleeding), and liver-related cognitive impairment (hepatic encephalopathy).

How Much Does Fatty Liver Treatment Cost in Singapore

The cost of managing fatty liver in Singapore varies depending on the type of diagnostic tests, treatment required, healthcare setting, and overall complexity of care.

Treatment Type

Cost

Liver Function Blood Tests

SGD 30 – 100

Imaging Tests (Ultrasound)

SGD 150 – SGD 300

Imaging Tests (CT)

SGD 408 – SGD 956

Imaging Tests (MRI)

SGD 725 – SGD 1,869

Bariatric Surgery

SGD 3,952 – SGD 24,688

Actual costs may vary depending on the facility, complexity of care, and any additional tests or follow-ups required.

 

Fatty liver treatment costs in Singapore can vary based on:

Alternatives to Liver Transplant

For patients with advanced liver disease, ongoing research is exploring options that may reduce or delay the need for a liver transplant. These include therapies that support liver regeneration in cases of acute liver failure, as well as experimental approaches such as stem cell-based treatments.

 

While still under investigation, these alternatives may offer new avenues for managing fatty liver disease in the future.

Monitoring & Follow-Up

Ongoing monitoring by a specialist in Singapore is a crucial part of managing fatty liver disease. Regular tests, including liver enzyme checks and imaging, help track disease progression or improvement.

 

Follow-up care allows doctors to adjust treatment plans as needed, ensuring the best possible outcomes.

Dr Thng Yongxian, colorectal and general surgeon at private clinic Singapore

Dr Thng Yongxian

Senior Consultant

HEPATOPANCREATOBILIARY & GENERAL SURGEON

MBBS (SG) • MMed (Surg) • MRCS (Ire) • FRCSEd (Gen) • FAMS (Surg)

Dr Thng Yongxian is a fellowship-trained Hepatopancreatobiliary (HPB) & General Surgeon with a clinical interest in liver disease, metabolic liver conditions, and advanced liver disease assessment, who has performed over 6,000 surgical procedures since 2008. He evaluates patients with fatty liver disease, including MASLD, MASH, hepatic steatosis, and fibrosis risk, and provides structured assessment and management plans tailored to the stage and severity of each patient’s condition.

Dr Thng pursued his subspecialty training at the Department of Hepatopancreatobiliary & Liver Transplant Surgery, Singapore General Hospital, before completing a clinical fellowship in Minimally Invasive HPB Surgery at Seoul National University Hospital in Bundang, South Korea. He further trained at Heidelberg University Hospital in Germany within the hepatobiliary and liver transplant department, providing him with clinical exposure to the full spectrum of advanced liver disease, from early-stage metabolic liver conditions through to complex cases requiring surgical intervention.

 

As an HPB surgeon, Dr Thng is well-placed to assess the progression of fatty liver disease across its stages, from early hepatic steatosis and MASLD to more advanced presentations involving significant fibrosis, cirrhosis risk, and liver function compromise.

 

He provides structured evaluation of disease severity and works with patients to explore appropriate management options, which may include lifestyle and nutritional guidance, medical management where appropriate, and close monitoring for disease progression. For patients whose condition has progressed to cirrhosis or advanced liver disease, Dr Thng is also equipped to assess associated complications, including the risk of liver tumours and hepatocellular carcinoma, which can arise in the setting of long-standing metabolic liver disease.

 

Where surgical assessment is warranted, Dr Thng draws on his extensive HPB surgical experience, including minimally invasive liver surgery and liver resection, having served as Consultant and Clinical Lead of the HPB Division at NTFGH, where he led the advancement of laparoscopic techniques for complex liver and pancreatic surgery. His clinical work in complex liver malignancy has been documented and published in peer-reviewed research under HPB, reflecting his experience with surgically demanding liver conditions.

 

Fatty liver disease is often a long-term condition, and Dr Thng understands that patients benefit most from consistent, coordinated care rather than a one-time assessment. He takes time to explain each patient’s findings clearly, discuss what the results mean for their health over time, and outline a management approach that feels practical and sustainable. Where other specialists are involved, he ensures care is well-coordinated so that patients receive integrated support from diagnosis through to ongoing monitoring and, where needed, treatment.

Professional Appointments
Educational Qualifications

Frequently Asked Questions About Fatty Liver Disease Treatment in Singapore

Can Fatty Liver Be Reversed?

Yes, in many cases, fatty liver disease can be reversed or improved with lifestyle changes, including weight loss, dietary adjustments, and regular exercise. Early intervention with the guidance of a specialist is key.

The timeline varies depending on the severity of the condition and the treatment approach. Improvements in liver fat and enzymes can often be seen within a few months with consistent lifestyle and medical management.

Fatty liver develops when excess fat accumulates in liver cells. Common causes include obesity, insulin resistance, type 2 diabetes, high cholesterol, and excessive alcohol intake.

Preventive measures focus on maintaining a healthy weight, following a balanced diet low in processed foods and added sugars, staying physically active, and limiting alcohol intake.

Fatty liver is often silent, but potential signs include fatigue, malaise, mild abdominal discomfort in the upper right abdomen, elevated liver enzymes in blood tests, and, in advanced cases, jaundice or swelling.

Corporate and Personal Insurance Plans

Our Clinic Location

Precision Surgical Centre
@ Gleneagles Hospital Annexe Block

Precision Surgical Centre @ Gleneagles Hospital Annexe Block

Clinic Locations

Nexus Surgical @ Mt. Alvernia

Nexus Surgical @ Mt. Elizabeth Orchard

Nexus Surgical @ Mt. Elizabeth Novena

Nexus Surgical @ Parkway East

Nexus Surgical @ Gleneagles Medical Centre

Nexus Surgical @ Mt. Alvernia

Nexus Surgical @ Mt. Elizabeth Orchard

Nexus Surgical @ Mt. Elizabeth Novena

Nexus Surgical @ Parkway East

Nexus Surgical @ Gleneagles Medical Centre

Nexus Surgical @ Mt. Alvernia

Nexus Surgical @ Mt. Elizabeth Orchard

Nexus Surgical @ Mt. Elizabeth Novena

Nexus Surgical @ Parkway East

Nexus Surgical @ Gleneagles Medical Centre

Need Help Navigating Your Health?

Dr. Thng Yongxian extensive surgical experience includes specialised expertise as both a liver cancer surgeon and a gallbladder specialist. If you wish to learn more about our fatty liver treatments or our other specialised treatments in Singapore, please contact our clinic today.